What are the diagnostic criteria of diabetes mellitus?
The WHO diagnostic criteria for diabetes mellitus:
Symptoms of diabetes plus ‘random’ blood glucose concentration 200 mg/dL, or
‘Fasting’ plasma glucose 126 mg/dL, or
‘2 hours-postload’ plasma glucose 200 mg/dL during an oral GTT (glucose
tolerance test), or
HbA1C 6.5%
The diagnostic criteria for pre-diabetes and diabetes are:
In these criteria, the categories of FPG (fasting plasma glucose) are:
FPG <100 mg/dL = Normal fasting glucose
FPG >100 mg/dL and <126 mg/dL = Impaired fasting glucose (IFG)
FPG >126 mg/dL = Provisional diagnosis of diabetes (of more than one occasion)
The corresponding categories when the oral GTT is used, are as follows:
In these criteria, the categories of 2 hPG (2-h postload glucose) are:
2 hPG <140 mg/dL = Normal glucose tolerance
2 hPG > 140 mg/dL and <200 mg/dL = Impaired glucose tolerance (IGT)
2 hPG >200 mg/dL = Provisional diagnosis of diabetes (must be confirmed on a
subsequent day)
NB: Patients with IGT (140–199 mg/dL), and/or IFG (100–125 mg/dL), or HbA1C
5.7–6.4% are now regarded as ‘pre-diabetes’.
Blood glucose concentration in mg/dL should be divided by 18 to get the value in
mmol/l, e.g. 140 mg/dL= 7.8 mmol/l.
Oral GTT is a test where the patient consumes 75 mg of glucose dissolved in 300 ml
of water in 5 minutes, after an unrestricted carbohydrate diet taken 3 days prior to the
test. A treated diabetic person may take his/her recommended meal instead of glucose.
Then blood and urine samples are collected every half-hourly for at least 2 hours.
HbA1C (or, glycosylated haemoglobin) provides an accurate and objective
measurement of blood glucose concentration for preceding 6–8 weeks.
The WHO diagnostic criteria for diabetes mellitus:
Symptoms of diabetes plus ‘random’ blood glucose concentration 200 mg/dL, or
‘Fasting’ plasma glucose 126 mg/dL, or
‘2 hours-postload’ plasma glucose 200 mg/dL during an oral GTT (glucose
tolerance test), or
HbA1C 6.5%
The diagnostic criteria for pre-diabetes and diabetes are:
In these criteria, the categories of FPG (fasting plasma glucose) are:
FPG <100 mg/dL = Normal fasting glucose
FPG >100 mg/dL and <126 mg/dL = Impaired fasting glucose (IFG)
FPG >126 mg/dL = Provisional diagnosis of diabetes (of more than one occasion)
The corresponding categories when the oral GTT is used, are as follows:
In these criteria, the categories of 2 hPG (2-h postload glucose) are:
2 hPG <140 mg/dL = Normal glucose tolerance
2 hPG > 140 mg/dL and <200 mg/dL = Impaired glucose tolerance (IGT)
2 hPG >200 mg/dL = Provisional diagnosis of diabetes (must be confirmed on a
subsequent day)
NB: Patients with IGT (140–199 mg/dL), and/or IFG (100–125 mg/dL), or HbA1C
5.7–6.4% are now regarded as ‘pre-diabetes’.
Blood glucose concentration in mg/dL should be divided by 18 to get the value in
mmol/l, e.g. 140 mg/dL= 7.8 mmol/l.
Oral GTT is a test where the patient consumes 75 mg of glucose dissolved in 300 ml
of water in 5 minutes, after an unrestricted carbohydrate diet taken 3 days prior to the
test. A treated diabetic person may take his/her recommended meal instead of glucose.
Then blood and urine samples are collected every half-hourly for at least 2 hours.
HbA1C (or, glycosylated haemoglobin) provides an accurate and objective
measurement of blood glucose concentration for preceding 6–8 weeks.